A randomized double-blind placebo-controlled phase 3 study to evaluate the efficacy and safety of estetrol for the treatment of moderate to severe vasomotor symptoms in postmenopausal women (E4Comfort Study I)

Financing : ICON

Researcher : Dr. Luis Bahamondes

Research Line : Sexual and Reproductive Health


The E4Comfort study is evaluating an oral drug to see if it can reduce hot flashes and night sweats in postmenopausal women. The study drug is Estetrol (E4) a naturally occurring synthetic form of estrogen.